2022 Acura MDX vs. 2022 Lexus RX

2022 Acura MDX vs. 2022 Lexus RX
2022 Acura MDX Standard


2022 Lexus RX 350
$48,000 MSRP*

Starting MSRP

$46,995 MSRP**
95 cubic feet

Maximum Cargo Capacity

56.3 cubic feet

Safety Technology

Lexus Safety System +
19 city mpg/26 hwy mpg**

Fuel Economy

20 city mpg/27 hwy mpg
3.5L V6 engine

Standard Engine

3.5L V6 engine
10-speed automatic transmission with Sequential SportShift Paddle Shifters


8-speed automatic electronically controlled transmission

If you’re in need of a spacious crossover to keep you moving around Costa Mesa and Tustin with ease, then you might be looking at the 2022 Acura MDX or Lexus RX. The major difference between the 2022 Acura MDX and Lexus RX is pricing as the base MDX package starts at $48,000 MSRP while the Lexus RX has a $46,995 MSRP. Despite the slightly higher price of the MDX, you’ll immediately find it offers upgraded features over the RX. Learn more about the 2022 Acura MDX vs. Lexus RX and then shop our inventory for your next luxury ride for sale at Weir Canyon Acura today.



2022 Acura MDX or Lexus RX: Fuel Economy & Performance

As you compare luxury SUVs, you need to ensure you have plenty of power to keep you moving around Tustin and Montclair. Both models feature a similar base V6 engine configuration, while the MDX takes the lead by offering a more powerful transmission as well as the ability to upgrade to the brand’s own celebrated and available Super-Handling All-Wheel Drive system. See for yourself the base performance specs of the 2022 Acura MDX vs. Lexus RX below:

2022 Acura MDX FWD Standard Package

  • 3.5L V6 engine
  • 10-speed automatic transmission
  • 19 city mpg/26 hwy mpg rating***

2022 Lexus RX 350

  • 3.5L V6 engine
  • 8-speed automatic electronically controlled transmission
  • 20 city mpg/27 hwy mpg rating

2022 Acura MDX or Lexus RX: Standard Features & Cabin Space

In terms of cabin features there are overlapping amenities in each luxury crossover SUV such as leather upholstery, Adaptive Cruise Control, satellite radio, and spacious seating for up to seven passengers. Where the MDX shines is its more spacious storage which measures 95 cubic feet cargo capacity compared to the RX 350 which only offers 56.3 cubic feet of cargo space. Plus, you’ll have features in the Acura MDX not found in the Lexus RX such as:

  • Heated front seats
  • Automatic tilt away steering column
  • Power moonroof
  • 2nd-row 60/40 split-folding bench seat

Compare Luxury SUVs for Sale at Weir Canyon Acura

After looking at the differences between the 2022 Acura MDX and Lexus RX 350, seal the deal on your next luxury SUV near Montclair. Bring home a new Acura MDX for sale from Weir Canyon Acura and see how you can save even more on your next ride when you shop our inventory of national offers and incentives. Speak with our sales team if you have any questions or you can apply for financing online from home to get started. Contact us today for more information on the 2022 Acura MDX vs. Lexus RX and schedule your test drive at our dealership right here in Anaheim!

*Prices shown are Acura suggested retail prices only and do not include taxes, license or destination and handling charge. Destination & Handling charge for sedans (excluding PMC Edition) is $1,095 and SUVs (excluding PMC Edition) is $1,195.00. Destination & Handling charge for PMC Edition models and NSX is $1,995.00. Premium Paint colors are $500 and not included.Acura vehicle accessory costs, labor and installation vary. Dealers set their own prices. Please consult your selected dealer.

** Based on 2022 EPA mileage ratings. Used for comparison purposes only. Your actual mileage will vary, depending on how you drive and maintain your vehicle, driving conditions, battery pack age/condition (hybrid only) and other factors


More from Weir Canyon Acura

  • 2024 Acura TLX MPG

    Looking for a sporty sedan with some zip and outstanding fuel efficiency? You’ll love the 2024 Acura TLX mpg ratings for your Costa Mesa drives. This car has outstanding power with its turbocharged engine choices to go along with Super Handling-All Wheel Drive (SH-AWD) capabilities for slick roads. Keep reading this guide to the 2024 Acura…

  • 2024 Acura Integra 0-60 Time

    Ready to put a high-performance sedan in your Costa Mesa garage? Look no further than the 2024 Acura Integra, a stalwart of the brand for decades. It’s got everything a modern driver wants in a new vehicle, from a high-tech interior to a speedy engine.  Our guide to the 2024 Acura Integra 0-60 time covers much…

  • 2024 Acura RDX MPG

      Acura vehicles are high-performing, premium vehicles that will transform the way you enjoy your drives around Costa Mesa and Tustin. If you’re searching for a vehicle that can deliver high-end performance and impressive fuel efficiency, you’d want to take a look at the new Acura RDX. The 2024 Acura RDX mpg for its base trim…

Weir Canyon Acura 33.8769357, -117.75044.